Evidence for prejunctional inhibitory muscarinic receptors on sympathetic nerves innervating guinea-pig trachealis muscle
نویسندگان
چکیده
منابع مشابه
Evidence for nonadrenergic inhibitory nerves in the guinea pig trachealis muscle.
COBURN, R. F., AND T. TOMITA. Evidence for nonadrenergic inhibitory nerves in the guinea pig trachealis muscle. Am. J. Physiol. 224(5) : 1072-1080. 1973-The inhibitory innervation of the guinea pig trachealis muscle was studied by placing muscle strips in an organ bath containing Krebs solution equilibrated with 97 y. 02 and 3 To CO2 and measuring the effects of field stimulation on isometric t...
متن کاملthe inhibitory effects of ferula assafoetida on muscarinic receptors of guinea-pig tracheal smooth muscle
conclusions these results showed an inhibitory effect for the extract of asafetida on muscarinic receptors of tracheal smooth muscle. results the ec50 obtained in the presence of higher concentration of the extract muscle was significantly higher compared to saline (p < 0.01). the maximum responses to methacholine in the presence of higher concentration of the extract (10 mg/ml) was significant...
متن کاملParainfluenza virus infection damages inhibitory M2 muscarinic receptors on pulmonary parasympathetic nerves in the guinea-pig.
1. The effect of viral infection on the function of neuronal M2 muscarinic autoreceptors in the lungs was studied in anaesthetized guinea-pigs. 2. Guinea-pigs were inoculated intranasally with either parainfluenza type 3 or with a vehicle control. Four days later the animals were anaesthetized, paralysed and artificially ventilated. Pulmonary inflation pressure, tidal volume, blood pressure, an...
متن کاملHeterogeneity of release-regulating muscarinic receptors in rat sympathetic neurons: evidence for inhibitory presynaptic M1 receptors
Of the 5 known subtypes of mAChRs, M2, M3, and M4 have been reported to act as inhibitory presynaptic receptors in the nervous system, in general, and in sympathetic neurons, in particular. M1 receptors, in contrast, have rather been viewed as facilitatory presynaptic receptors. In superior cervical ganglion (SCG) neurons, M1 receptors are well known to inhibit KCNQ channels. Previously, we wer...
متن کاملPrimary afferent neurons innervating guinea pig dura.
We made recordings from filaments of guinea pig nasociliary nerve to study response properties of afferent axons innervating the anterior superior sagittal sinus and surrounding dura mater. We analyzed 38 units in 14 experiments. Units were initially located with the use of mechanical stimuli, and were then characterized by their conduction velocity and sensitivities to mechanical, thermal, and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1991
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1991.tb12318.x